Emily Bakker Is dietary nitrate supplementation necessary to ensure proper endothelial function at altitude ?
نویسندگان
چکیده
Introduction: At altitude the body is exposed to systemic hypobaric hypoxia and adapts in order
منابع مشابه
“Beet-ing” the Mountain: A Review of the Physiological and Performance Effects of Dietary Nitrate Supplementation at Simulated and Terrestrial Altitude
Exposure to altitude results in multiple physiological consequences. These include, but are not limited to, a reduced maximal oxygen consumption, drop in arterial oxygen saturation, and increase in muscle metabolic perturbations at a fixed sub-maximal work rate. Exercise capacity during fixed work rate or incremental exercise and time-trial performance are also impaired at altitude relative to ...
متن کاملEffects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study
Nitric oxide (NO) production plays a central role in conferring tolerance to hypoxia. Tibetan highlanders, successful high-altitude dwellers for millennia, have higher circulating nitrate and exhaled NO (ENO) levels than native lowlanders. Since nitrate itself can reduce the oxygen cost of exercise in normoxia it may confer additional benefits at high altitude. Xtreme Alps was a double-blinded ...
متن کاملDesign and conduct of 'Xtreme Alps': a double-blind, randomised controlled study of the effects of dietary nitrate supplementation on acclimatisation to high altitude.
The study of healthy human volunteers ascending to high altitude provides a robust model of the complex physiological interplay that emulates human adaptation to hypoxaemia in clinical conditions. Nitric oxide (NO) metabolism may play an important role in both adaptation to high altitude and response to hypoxaemia during critical illness at sea level. Circulating nitrate and nitrite concentrati...
متن کاملEffects of Dietary Nitrate Supplementation on Physiological Responses, Cognitive Function, and Exercise Performance at Moderate and Very-High Simulated Altitude
Purpose: Nitric oxide (NO) bioavailability is reduced during acute altitude exposure, contributing toward the decline in physiological and cognitive function in this environment. This study evaluated the effects of nitrate ([Formula: see text]) supplementation on NO bioavailability, physiological and cognitive function, and exercise performance at moderate and very-high simulated altitude. Meth...
متن کاملAcute Dietary Nitrate Supplementation Decreases Systolic Blood Pressure and Increases Dry Static Apnea Performance in Females
Collofello BS, Moskalik B, Essick EE. Acute Dietary Nitrate Supplementation Decreases Systolic Blood Pressure and Increases Dry Static Apnea Performance in Females. JEPonline 2014;17(4):1526. Recently, dietary inorganic nitrate has been explored as a sports nutrition supplement, and has been shown to enhance exercise performance by reducing metabolic oxygen cost and lowering blood pressure. The...
متن کامل